1tbg: Difference between revisions

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[[Image:1tbg.png|left|200px]]


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==BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN==
The line below this paragraph, containing "STRUCTURE_1tbg", creates the "Structure Box" on the page.
<StructureSection load='1tbg' size='340' side='right'caption='[[1tbg]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1tbg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2004 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''G Proteins''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2004_10 10.2210/rcsb_pdb/mom_2004_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TBG FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tbg OCA], [https://pdbe.org/1tbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tbg RCSB], [https://www.ebi.ac.uk/pdbsum/1tbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tbg ProSAT]</span></td></tr>
{{STRUCTURE_1tbg| PDB=1tbg |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/GBB1_BOVIN GBB1_BOVIN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tb/1tbg_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tbg ConSurf].
<div style="clear:both"></div>


'''BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN'''
==See Also==
 
*[[Transducin 3D structures|Transducin 3D structures]]
 
__TOC__
{{ABSTRACT_8552196}}
</StructureSection>
 
==About this Structure==
1TBG is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The following page contains interesting information on the relation of 1TBG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb58_1.html G Proteins]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TBG OCA].
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: G Proteins]]
[[Category: G Proteins]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Bohm, A.]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Hamm, H E.]]
[[Category: Bohm A]]
[[Category: Lambright, D G.]]
[[Category: Hamm HE]]
[[Category: Sigler, P B.]]
[[Category: Lambright DG]]
[[Category: Sondek, J S.]]
[[Category: Sigler PB]]
[[Category: Eye]]
[[Category: Sondek JS]]
[[Category: Prenylation]]
[[Category: Transducer]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 18:00:00 2008''
Retrieved from "https://proteopedia.org/1tbg"