1a7t: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1a7t.png|left|200px]]


<!--
==METALLO-BETA-LACTAMASE WITH MES==
The line below this paragraph, containing "STRUCTURE_1a7t", creates the "Structure Box" on the page.
<StructureSection load='1a7t' size='340' side='right'caption='[[1a7t]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1a7t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_fragilis Bacteroides fragilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A7T FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1a7t| PDB=1a7t |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a7t OCA], [https://pdbe.org/1a7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a7t RCSB], [https://www.ebi.ac.uk/pdbsum/1a7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a7t ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAB_BACFG BLAB_BACFG] Can hydrolyze carbapenem compounds.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a7/1a7t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a7t ConSurf].
<div style="clear:both"></div>


===METALLO-BETA-LACTAMASE WITH MES===
==See Also==
 
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
 
__TOC__
<!--  
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_9578564}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9578564 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_9578564}}
 
==About this Structure==
1A7T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_fragilis Bacteroides fragilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7T OCA].
 
==Reference==
Unanticipated inhibition of the metallo-beta-lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): a crystallographic study at 1.85-A resolution., Fitzgerald PM, Wu JK, Toney JH, Biochemistry. 1998 May 12;37(19):6791-800. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9578564 9578564]
[[Category: Bacteroides fragilis]]
[[Category: Bacteroides fragilis]]
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Fitzgerald PMD]]
[[Category: Fitzgerald, P M.D.]]
[[Category: Toney JH]]
[[Category: Toney, J H.]]
[[Category: Wu JK]]
[[Category: Wu, J K.]]
[[Category: Metallo beta-lactamase]]
[[Category: Zinc]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:19:56 2008''

Latest revision as of 06:28, 7 February 2024

METALLO-BETA-LACTAMASE WITH MES

1a7t, resolution 1.85Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1a7t&oldid=4039955"