1aca: Difference between revisions

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{{Seed}}
[[Image:1aca.png|left|200px]]


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==THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN ACYL-COENZYME A BINDING PROTEIN AND PALMITOYL-COENZYME A==
The line below this paragraph, containing "STRUCTURE_1aca", creates the "Structure Box" on the page.
<StructureSection load='1aca' size='340' side='right'caption='[[1aca]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1aca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ACA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ACA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
{{STRUCTURE_1aca|  PDB=1aca  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aca OCA], [https://pdbe.org/1aca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aca RCSB], [https://www.ebi.ac.uk/pdbsum/1aca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aca ProSAT]</span></td></tr>
 
</table>
===THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN ACYL-COENZYME A BINDING PROTEIN AND PALMITOYL-COENZYME A===
== Function ==
 
[https://www.uniprot.org/uniprot/ACBP_BOVIN ACBP_BOVIN] Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.<ref>PMID:11491287</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_8503960}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 8503960 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ac/1aca_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_8503960}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1ACA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ACA OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1aca ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Three-dimensional structure of the complex between acyl-coenzyme A binding protein and palmitoyl-coenzyme A., Kragelund BB, Andersen KV, Madsen JC, Knudsen J, Poulsen FM, J Mol Biol. 1993 Apr 20;230(4):1260-77. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8503960 8503960]
<references/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Andersen, K V.]]
[[Category: Andersen KV]]
[[Category: Knudsen, J.]]
[[Category: Knudsen J]]
[[Category: Kragelund, B B.]]
[[Category: Kragelund BB]]
[[Category: Madsen, J C.]]
[[Category: Madsen JC]]
[[Category: Poulsen, F M.]]
[[Category: Poulsen FM]]
[[Category: Acyl-coenzyme a binding protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:34:17 2008''

Latest revision as of 15:23, 13 March 2024

THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN ACYL-COENZYME A BINDING PROTEIN AND PALMITOYL-COENZYME A

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