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New page: left|200px<br /><applet load="1dty" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dty, resolution 2.14Å" /> '''CRYSTAL STRUCTURE OF...
 
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[[Image:1dty.gif|left|200px]]<br /><applet load="1dty" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1dty, resolution 2.14&Aring;" />
'''CRYSTAL STRUCTURE OF ADENOSYLMETHIONINE-8-AMINO-7-OXONANOATE AMINOTRANSFERASE WITH PYRIDOXAL PHOSPHATE COFACTOR.'''<br />


==About this Structure==
==CRYSTAL STRUCTURE OF ADENOSYLMETHIONINE-8-AMINO-7-OXONANOATE AMINOTRANSFERASE WITH PYRIDOXAL PHOSPHATE COFACTOR.==
1DTY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with NA and PLP as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenosylmethionine--8-amino-7-oxononanoate_transaminase Adenosylmethionine--8-amino-7-oxononanoate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.62 2.6.1.62] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DTY OCA].  
<StructureSection load='1dty' size='340' side='right'caption='[[1dty]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
[[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1dty]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dty OCA], [https://pdbe.org/1dty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dty RCSB], [https://www.ebi.ac.uk/pdbsum/1dty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dty ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BIOA_ECOLI BIOA_ECOLI] Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.<ref>PMID:1092681</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/1dty_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dty ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[7%2C8-diaminopelargonic acid synthase 3D structures|7%2C8-diaminopelargonic acid synthase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Alexeev, D.]]
[[Category: Alexeev D]]
[[Category: Alexeeva, M.V.]]
[[Category: Alexeeva MV]]
[[Category: Baxter, R.L.]]
[[Category: Baxter RL]]
[[Category: Campopiano, D.]]
[[Category: Campopiano D]]
[[Category: Sawyer, L.]]
[[Category: Sawyer L]]
[[Category: NA]]
[[Category: PLP]]
[[Category: biotin biosynthesis]]
[[Category: dapa]]
[[Category: diaminonanonoic acid]]
[[Category: diaminopelargonic acid]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 13:34:41 2007''
Retrieved from "https://proteopedia.org/1dty"