1awc: Difference between revisions

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{{Seed}}
[[Image:1awc.png|left|200px]]


<!--
==MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA==
The line below this paragraph, containing "STRUCTURE_1awc", creates the "Structure Box" on the page.
<StructureSection load='1awc' size='340' side='right'caption='[[1awc]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1awc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AWC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene></td></tr>
{{STRUCTURE_1awc|  PDB=1awc  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1awc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1awc OCA], [https://pdbe.org/1awc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1awc RCSB], [https://www.ebi.ac.uk/pdbsum/1awc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1awc ProSAT]</span></td></tr>
 
</table>
===MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA===
== Function ==
 
[https://www.uniprot.org/uniprot/GABPA_MOUSE GABPA_MOUSE] Transcription factor capable of interacting with purine rich repeats (GA repeats).
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_9461436}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 9461436 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aw/1awc_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_9461436}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1AWC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AWC OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1awc ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA., Batchelor AH, Piper DE, de la Brousse FC, McKnight SL, Wolberger C, Science. 1998 Feb 13;279(5353):1037-41. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9461436 9461436]
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Batchelor AH]]
[[Category: Batchelor, A H.]]
[[Category: Wolberger C]]
[[Category: Wolberger, C.]]
[[Category: Ankyrin repeat]]
[[Category: Dna-binding]]
[[Category: Ets domain]]
[[Category: Nuclear protein]]
[[Category: Transcription factor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:44:28 2008''
Retrieved from "https://proteopedia.org/1awc"