1ayr: Difference between revisions

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{{Seed}}
[[Image:1ayr.png|left|200px]]


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==ARRESTIN FROM BOVINE ROD OUTER SEGMENTS==
The line below this paragraph, containing "STRUCTURE_1ayr", creates the "Structure Box" on the page.
<StructureSection load='1ayr' size='340' side='right'caption='[[1ayr]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ayr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AYR FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ayr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ayr OCA], [https://pdbe.org/1ayr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ayr RCSB], [https://www.ebi.ac.uk/pdbsum/1ayr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ayr ProSAT]</span></td></tr>
{{STRUCTURE_1ayr| PDB=1ayr |  SCENE= }}
</table>
== Disease ==
[https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis.
== Function ==
[https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ay/1ayr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ayr ConSurf].
<div style="clear:both"></div>


===ARRESTIN FROM BOVINE ROD OUTER SEGMENTS===
==See Also==
 
*[[Arrestin 3D structures|Arrestin 3D structures]]
 
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(as it appears on PubMed at http://www.pubmed.gov), where 9495348 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9495348}}
 
==About this Structure==
1AYR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AYR OCA].
 
==Reference==
X-ray crystal structure of arrestin from bovine rod outer segments., Granzin J, Wilden U, Choe HW, Labahn J, Krafft B, Buldt G, Nature. 1998 Feb 26;391(6670):918-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9495348 9495348]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bueldt, G.]]
[[Category: Bueldt G]]
[[Category: Choe, H W.]]
[[Category: Choe H-W]]
[[Category: Granzin, J.]]
[[Category: Granzin J]]
[[Category: Krafft, B.]]
[[Category: Krafft B]]
[[Category: Labahn, J.]]
[[Category: Labahn J]]
[[Category: Wilden, U.]]
[[Category: Wilden U]]
[[Category: Arrestin]]
[[Category: Rhodopsin]]
[[Category: Sensory transduction]]
 
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