1c1k: Difference between revisions

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{{Seed}}
[[Image:1c1k.png|left|200px]]


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==BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN==
The line below this paragraph, containing "STRUCTURE_1c1k", creates the "Structure Box" on the page.
<StructureSection load='1c1k' size='340' side='right'caption='[[1c1k]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1c1k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C1K FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IR:IRIDIUM+ION'>IR</scene></td></tr>
{{STRUCTURE_1c1k|  PDB=1c1k  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c1k OCA], [https://pdbe.org/1c1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c1k RCSB], [https://www.ebi.ac.uk/pdbsum/1c1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c1k ProSAT]</span></td></tr>
 
</table>
===BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN===
== Function ==
 
[https://www.uniprot.org/uniprot/HLOAD_BPT4 HLOAD_BPT4] DNA helicase loader protein that participates in viral DNA replication, recombination, and repair (PubMed:10871615). At the fork, required for loading of the replicative helicase onto DNA protected by the ssDNA-binding protein (PubMed:11459967, PubMed:7806533, PubMed:10871615, PubMed:22427673). Coordinates simultaneous synthesis of leading- and lagging-strands (PubMed:11459969).[HAMAP-Rule:MF_04156]<ref>PMID:10871615</ref> <ref>PMID:11459967</ref> <ref>PMID:22427673</ref> <ref>PMID:7806533</ref> <ref>PMID:11459969</ref>
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_10669611}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 10669611 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c1/1c1k_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10669611}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1C1K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C1K OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c1k ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Bacteriophage T4 gene 59 helicase assembly protein binds replication fork DNA. The 1.45 A resolution crystal structure reveals a novel alpha-helical two-domain fold., Mueser TC, Jones CE, Nossal NG, Hyde CC, J Mol Biol. 2000 Feb 18;296(2):597-612. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10669611 10669611]
<references/>
[[Category: Enterobacteria phage t4]]
__TOC__
[[Category: Single protein]]
</StructureSection>
[[Category: Hyde, C C.]]
[[Category: Escherichia virus T4]]
[[Category: Jones, C E.]]
[[Category: Large Structures]]
[[Category: Mueser, T C.]]
[[Category: Hyde CC]]
[[Category: Nossal, N G.]]
[[Category: Jones CE]]
[[Category: Dna recombination]]
[[Category: Mueser TC]]
[[Category: Dna replication]]
[[Category: Nossal NG]]
[[Category: Forked dna]]
[[Category: Helicase assembly]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:04:59 2008''

Latest revision as of 06:40, 7 February 2024

BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN

1c1k, resolution 1.45Å

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