1col: Difference between revisions

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[[Image:1col.png|left|200px]]


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==REFINED STRUCTURE OF THE PORE-FORMING DOMAIN OF COLICIN A AT 2.4 ANGSTROMS RESOLUTION==
The line below this paragraph, containing "STRUCTURE_1col", creates the "Structure Box" on the page.
<StructureSection load='1col' size='340' side='right'caption='[[1col]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1col]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1COL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1col FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1col OCA], [https://pdbe.org/1col PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1col RCSB], [https://www.ebi.ac.uk/pdbsum/1col PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1col ProSAT]</span></td></tr>
{{STRUCTURE_1col| PDB=1col |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CEA_ECOLX CEA_ECOLX] This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.<ref>PMID:2434951</ref>  Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.<ref>PMID:2434951</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/1col_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1col ConSurf].
<div style="clear:both"></div>


===REFINED STRUCTURE OF THE PORE-FORMING DOMAIN OF COLICIN A AT 2.4 ANGSTROMS RESOLUTION===
==See Also==
 
*[[Colicin 3D structures|Colicin 3D structures]]
 
== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 1373773 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1373773}}
 
==About this Structure==
1COL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COL OCA].
 
==Reference==
Refined structure of the pore-forming domain of colicin A at 2.4 A resolution., Parker MW, Postma JP, Pattus F, Tucker AD, Tsernoglou D, J Mol Biol. 1992 Apr 5;224(3):639-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1373773 1373773]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Parker, M W.]]
[[Category: Parker MW]]
[[Category: Pattus, F.]]
[[Category: Pattus F]]
[[Category: Postma, J P.M.]]
[[Category: Postma JPM]]
[[Category: Tsernoglou, D.]]
[[Category: Tsernoglou D]]
[[Category: Tucker, A D.]]
[[Category: Tucker AD]]
[[Category: Antibacterial protein]]
 
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