1dc9: Difference between revisions

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{{Seed}}
[[Image:1dc9.png|left|200px]]


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==PROPERTIES AND CRYSTAL STRUCTURE OF A BETA-BARREL FOLDING MUTANT, V60N INTESTINAL FATTY ACID BINDING PROTEIN (IFABP)==
The line below this paragraph, containing "STRUCTURE_1dc9", creates the "Structure Box" on the page.
<StructureSection load='1dc9' size='340' side='right'caption='[[1dc9]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dc9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DC9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dc9 OCA], [https://pdbe.org/1dc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dc9 RCSB], [https://www.ebi.ac.uk/pdbsum/1dc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dc9 ProSAT]</span></td></tr>
{{STRUCTURE_1dc9| PDB=1dc9 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/FABPI_RAT FABPI_RAT] FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dc/1dc9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dc9 ConSurf].
<div style="clear:both"></div>


===PROPERTIES AND CRYSTAL STRUCTURE OF A BETA-BARREL FOLDING MUTANT, V60N INTESTINAL FATTY ACID BINDING PROTEIN (IFABP)===
==See Also==
 
*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_10692339}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 10692339 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10692339}}
 
==About this Structure==
1DC9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DC9 OCA].
 
==Reference==
Properties and crystal structure of a beta-barrel folding mutant., Ropson IJ, Yowler BC, Dalessio PM, Banaszak L, Thompson J, Biophys J. 2000 Mar;78(3):1551-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10692339 10692339]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Banaszak L]]
[[Category: Banaszak, L.]]
[[Category: Dalessio PM]]
[[Category: Dalessio, P M.]]
[[Category: Ropson IJ]]
[[Category: Ropson, I J.]]
[[Category: Thompson J]]
[[Category: Thompson, J.]]
[[Category: Yowler BC]]
[[Category: Yowler, B C.]]
[[Category: Beta- barrel]]
[[Category: Fatty acid binding protein]]
[[Category: Intracellular lipid binding protein]]
[[Category: Mutant]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:48:41 2008''

Latest revision as of 06:51, 7 February 2024

PROPERTIES AND CRYSTAL STRUCTURE OF A BETA-BARREL FOLDING MUTANT, V60N INTESTINAL FATTY ACID BINDING PROTEIN (IFABP)

1dc9, resolution 2.10Å

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