1ddk: Difference between revisions

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{{Seed}}
[[Image:1ddk.png|left|200px]]


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==CRYSTAL STRUCTURE OF IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA==
The line below this paragraph, containing "STRUCTURE_1ddk", creates the "Structure Box" on the page.
<StructureSection load='1ddk' size='340' side='right'caption='[[1ddk]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ddk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DDK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1ddk| PDB=1ddk |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ddk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ddk OCA], [https://pdbe.org/1ddk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ddk RCSB], [https://www.ebi.ac.uk/pdbsum/1ddk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ddk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q79MP6_PSEAI Q79MP6_PSEAI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dd/1ddk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ddk ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA===
==See Also==
 
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
 
__TOC__
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</StructureSection>
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[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 10757977 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10757977}}
 
==About this Structure==
1DDK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DDK OCA].
 
==Reference==
Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor., Concha NO, Janson CA, Rowling P, Pearson S, Cheever CA, Clarke BP, Lewis C, Galleni M, Frere JM, Payne DJ, Bateson JH, Abdel-Meguid SS, Biochemistry. 2000 Apr 18;39(15):4288-98. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10757977 10757977]
[[Category: Beta-lactamase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Single protein]]
[[Category: Abdel-Meguid SS]]
[[Category: Abdel-Meguid, S S.]]
[[Category: Bateson JH]]
[[Category: Bateson, J H.]]
[[Category: Cheever CA]]
[[Category: Cheever, C A.]]
[[Category: Clarke BP]]
[[Category: Clarke, B P.]]
[[Category: Concha NO]]
[[Category: Concha, N O.]]
[[Category: Frere JM]]
[[Category: Frere, J M.]]
[[Category: Galleni M]]
[[Category: Galleni, M.]]
[[Category: Janson CA]]
[[Category: Janson, C A.]]
[[Category: Lewis C]]
[[Category: Lewis, C.]]
[[Category: Payne DJ]]
[[Category: Payne, D J.]]
[[Category: Pearson S]]
[[Category: Pearson, S.]]
[[Category: Rowling P]]
[[Category: Rowling, P.]]
[[Category: Binuclear metal center]]
[[Category: Imp-1 metallo beta-lactamase]]
[[Category: X-ray crystallography]]
[[Category: Zn beta-lactamase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:51:54 2008''