1dpr: Difference between revisions

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[[Image:1dpr.png|left|200px]]


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==STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE==
The line below this paragraph, containing "STRUCTURE_1dpr", creates the "Structure Box" on the page.
<StructureSection load='1dpr' size='340' side='right'caption='[[1dpr]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dpr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPR FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpr OCA], [https://pdbe.org/1dpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpr RCSB], [https://www.ebi.ac.uk/pdbsum/1dpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpr ProSAT]</span></td></tr>
{{STRUCTURE_1dpr|  PDB=1dpr |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DTXR_CORDI DTXR_CORDI] Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/1dpr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dpr ConSurf].
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===STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE===
==See Also==
 
*[[Diphtheria toxin repressor|Diphtheria toxin repressor]]
 
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{{ABSTRACT_PUBMED_7568230}}
 
==About this Structure==
1DPR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPR OCA].
 
==Reference==
Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae., Schiering N, Tao X, Zeng H, Murphy JR, Petsko GA, Ringe D, Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9843-50. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7568230 7568230]
[[Category: Corynebacterium diphtheriae]]
[[Category: Corynebacterium diphtheriae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Murphy, J.]]
[[Category: Murphy J]]
[[Category: Petsko, G A.]]
[[Category: Petsko GA]]
[[Category: Ringe, D.]]
[[Category: Ringe D]]
[[Category: Schiering, N.]]
[[Category: Schiering N]]
[[Category: Tao, X.]]
[[Category: Tao X]]
[[Category: Diphtheria]]
[[Category: Dna-binding]]
[[Category: Iron-regulation repressor]]
[[Category: Virulence]]
 
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