1ehi: Difference between revisions

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{{Seed}}
[[Image:1ehi.png|left|200px]]


<!--
==D-ALANINE:D-LACTATE LIGASE (LMDDL2) OF VANCOMYCIN-RESISTANT LEUCONOSTOC MESENTEROIDES==
The line below this paragraph, containing "STRUCTURE_1ehi", creates the "Structure Box" on the page.
<StructureSection load='1ehi' size='340' side='right'caption='[[1ehi]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ehi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leuconostoc_mesenteroides Leuconostoc mesenteroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EHI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PHY:1(S)-AMINOETHYL-(2-CARBOXYPROPYL)PHOSPHORYL-PHOSPHINIC+ACID'>PHY</scene></td></tr>
{{STRUCTURE_1ehi|  PDB=1ehi  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ehi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ehi OCA], [https://pdbe.org/1ehi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ehi RCSB], [https://www.ebi.ac.uk/pdbsum/1ehi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ehi ProSAT]</span></td></tr>
 
</table>
===D-ALANINE:D-LACTATE LIGASE (LMDDL2) OF VANCOMYCIN-RESISTANT LEUCONOSTOC MESENTEROIDES===
== Function ==
 
[https://www.uniprot.org/uniprot/DDL_LEUMM DDL_LEUMM] Cell wall formation.[HAMAP-Rule:MF_00047]
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_10801495}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 10801495 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/1ehi_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10801495}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1EHI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Leuconostoc_mesenteroides Leuconostoc mesenteroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EHI OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ehi ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Enzymes of vancomycin resistance: the structure of D-alanine-D-lactate ligase of naturally resistant Leuconostoc mesenteroides., Kuzin AP, Sun T, Jorczak-Baillass J, Healy VL, Walsh CT, Knox JR, Structure. 2000 May 15;8(5):463-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10801495 10801495]
</StructureSection>
[[Category: D-alanine--D-alanine ligase]]
[[Category: Large Structures]]
[[Category: Leuconostoc mesenteroides]]
[[Category: Leuconostoc mesenteroides]]
[[Category: Single protein]]
[[Category: Healy VL]]
[[Category: Healy, V L.]]
[[Category: Jorczak-Baillass J]]
[[Category: Jorczak-Baillass, J.]]
[[Category: Knox JR]]
[[Category: Knox, J R.]]
[[Category: Kuzin AP]]
[[Category: Kuzin, A P.]]
[[Category: Sun T]]
[[Category: Sun, T.]]
[[Category: Walsh CT]]
[[Category: Walsh, C T.]]
[[Category: Atp-binding. grasp motif for atp.]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 00:42:35 2008''

Latest revision as of 07:03, 7 February 2024

D-ALANINE:D-LACTATE LIGASE (LMDDL2) OF VANCOMYCIN-RESISTANT LEUCONOSTOC MESENTEROIDES

1ehi, resolution 2.38Å

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