1esj: Difference between revisions

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[[Image:1esj.png|left|200px]]


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==CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S)==
The line below this paragraph, containing "STRUCTURE_1esj", creates the "Structure Box" on the page.
<StructureSection load='1esj' size='340' side='right'caption='[[1esj]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1esj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ESJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1esj|  PDB=1esj  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1esj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1esj OCA], [https://pdbe.org/1esj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1esj RCSB], [https://www.ebi.ac.uk/pdbsum/1esj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1esj ProSAT]</span></td></tr>
 
</table>
===CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S)===
== Function ==
 
[https://www.uniprot.org/uniprot/THIM_BACSU THIM_BACSU]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_10891066}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/es/1esj_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10891066}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1ESJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESJ OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1esj ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution., Campobasso N, Mathews II, Begley TP, Ealick SE, Biochemistry. 2000 Jul 11;39(27):7868-77. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10891066 10891066]
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Hydroxyethylthiazole kinase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Begley TP]]
[[Category: Begley, T P.]]
[[Category: Campobasso N]]
[[Category: Campobasso, N.]]
[[Category: Ealick SE]]
[[Category: Ealick, S E.]]
[[Category: Mathews II]]
[[Category: Mathews, I I.]]
[[Category: Alpha-beta protein]]
[[Category: Trimer]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 01:49:24 2008''