1etz: Difference between revisions

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{{Seed}}
[[Image:1etz.png|left|200px]]


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==THE THREE-DIMENSIONAL STRUCTURE OF AN ANTI-SWEETENER FAB, NC10.14, SHOWS THE EXTENT OF STRUCTURAL DIVERSITY IN ANTIGEN RECOGNITION BY IMMUNOGLOBULINS==
The line below this paragraph, containing "STRUCTURE_1etz", creates the "Structure Box" on the page.
<StructureSection load='1etz' size='340' side='right'caption='[[1etz]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1etz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ETZ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAS:N-(P-CYANOPHENYL)-N-DIPHENYLMETHYL-GUANIDINE-ACETIC+ACID'>GAS</scene></td></tr>
{{STRUCTURE_1etz| PDB=1etz |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1etz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1etz OCA], [https://pdbe.org/1etz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1etz RCSB], [https://www.ebi.ac.uk/pdbsum/1etz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1etz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/G0YP42_MOUSE G0YP42_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/et/1etz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1etz ConSurf].
<div style="clear:both"></div>


===THE THREE-DIMENSIONAL STRUCTURE OF AN ANTI-SWEETENER FAB, NC10.14, SHOWS THE EXTENT OF STRUCTURAL DIVERSITY IN ANTIGEN RECOGNITION BY IMMUNOGLOBULINS===
==See Also==
 
*[[Antibody 3D structures|Antibody 3D structures]]
 
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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The line below this paragraph, {{ABSTRACT_PUBMED_10993728}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 10993728 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Mus musculus]]
{{ABSTRACT_PUBMED_10993728}}
[[Category: Anchin JM]]
 
[[Category: Broomell C]]
==About this Structure==
[[Category: Edmundson AB]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETZ OCA].
[[Category: Fan Z]]
 
[[Category: Guddat LW]]
==Reference==
[[Category: Linthicum DS]]
The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins., Guddat LW, Shan L, Broomell C, Ramsland PA, Fan Z, Anchin JM, Linthicum DS, Edmundson AB, J Mol Biol. 2000 Sep 29;302(4):853-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10993728 10993728]
[[Category: Ramsland PA]]
[[Category: Anchin, J M.]]
[[Category: Shan L]]
[[Category: Broomell, C.]]
[[Category: Edmundson, A B.]]
[[Category: Fan, Z.]]
[[Category: Guddat, L W.]]
[[Category: Linthicum, D S.]]
[[Category: Ramsland, P A.]]
[[Category: Shan, L.]]
[[Category: Anti-sweetener fab]]
[[Category: Antigen recognition]]
[[Category: Antigen-antibody]]
[[Category: Complex]]
[[Category: Crystal structure]]
[[Category: Receptor mimicry]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 01:59:18 2008''
Retrieved from "https://proteopedia.org/1etz"