1eu5: Difference between revisions

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{{Seed}}
[[Image:1eu5.png|left|200px]]


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==STRUCTURE OF E. COLI DUTPASE AT 1.45 A==
The line below this paragraph, containing "STRUCTURE_1eu5", creates the "Structure Box" on the page.
<StructureSection load='1eu5' size='340' side='right'caption='[[1eu5]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1eu5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EU5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_1eu5| PDB=1eu5 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eu5 OCA], [https://pdbe.org/1eu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eu5 RCSB], [https://www.ebi.ac.uk/pdbsum/1eu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eu5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DUT_ECOLI DUT_ECOLI] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/1eu5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eu5 ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF E. COLI DUTPASE AT 1.45 A===
==See Also==
 
*[[DUTPase 3D structures|DUTPase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11375495}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11375495 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11375495}}
 
==About this Structure==
1EU5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EU5 OCA].
 
==Reference==
Atomic resolution structure of Escherichia coli dUTPase determined ab initio., Gonzalez A, Larsson G, Persson R, Cedergren-Zeppezauer E, Acta Crystallogr D Biol Crystallogr. 2001 Jun;57(Pt 6):767-74. Epub 2001, May 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11375495 11375495]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: DUTP diphosphatase]]
[[Category: Cedergren-Zeppezauer E]]
[[Category: Cedergren-Zeppezauer, E.]]
[[Category: Gonzalez A]]
[[Category: Gonzalez, A.]]
[[Category: Larsson G]]
[[Category: Larsson, G.]]
[[Category: Persson R]]
[[Category: Persson, R.]]
[[Category: Distorted jelly roll]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 01:59:39 2008''
Retrieved from "https://proteopedia.org/1eu5"