1exb: Difference between revisions

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{{Seed}}
[[Image:1exb.png|left|200px]]


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==STRUCTURE OF THE CYTOPLASMIC BETA SUBUNIT-T1 ASSEMBLY OF VOLTAGE-DEPENDENT K CHANNELS==
The line below this paragraph, containing "STRUCTURE_1exb", creates the "Structure Box" on the page.
<StructureSection load='1exb' size='340' side='right'caption='[[1exb]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1exb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EXB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
{{STRUCTURE_1exb| PDB=1exb |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1exb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1exb OCA], [https://pdbe.org/1exb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1exb RCSB], [https://www.ebi.ac.uk/pdbsum/1exb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1exb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KCAB2_RAT KCAB2_RAT] Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/1exb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1exb ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF THE CYTOPLASMIC BETA SUBUNIT-T1 ASSEMBLY OF VOLTAGE-DEPENDENT K CHANNELS===
==See Also==
 
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
 
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[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 10884227 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10884227}}
 
==About this Structure==
1EXB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EXB OCA].
 
==Reference==
Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels., Gulbis JM, Zhou M, Mann S, MacKinnon R, Science. 2000 Jul 7;289(5476):123-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10884227 10884227]
[[Category: Protein complex]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Gulbis, J M.]]
[[Category: Gulbis JM]]
[[Category: MacKinnon, R.]]
[[Category: MacKinnon R]]
[[Category: Mann, S.]]
[[Category: Mann S]]
[[Category: Zhou, M.]]
[[Category: Zhou M]]
[[Category: Beta subunit]]
[[Category: Ion channel]]
[[Category: Oxidoreductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 02:09:48 2008''