1ezj: Difference between revisions

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{{Seed}}
[[Image:1ezj.png|left|200px]]


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==CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS==
The line below this paragraph, containing "STRUCTURE_1ezj", creates the "Structure Box" on the page.
<StructureSection load='1ezj' size='340' side='right'caption='[[1ezj]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ezj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sendai_virus_(strain_Harris) Sendai virus (strain Harris)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EZJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EMC:ETHYL+MERCURY+ION'>EMC</scene></td></tr>
{{STRUCTURE_1ezj|  PDB=1ezj  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ezj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ezj OCA], [https://pdbe.org/1ezj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ezj RCSB], [https://www.ebi.ac.uk/pdbsum/1ezj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ezj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PHOSP_SENDH PHOSP_SENDH] Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template.  Acts as a chaperone for newly synthesized free N protein, so-called N(0). Stabilizes the L protein upon binding it.
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The high resolution X-ray structure of the Sendai virus oligomerization domain reveals a homotetrameric coiled coil structure with many details that are different from classic coiled coils with canonical hydrophobic heptad repeats. Alternatives to the classic knobs-into-holes packing lead to differences in supercoil pitch and diameter that allow water molecules inside the core. This open and more hydrophilic structure does not seem to be destabilized by mutations that would be expected to disrupt classic coiled coils.


===CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS===
Tetrameric coiled coil domain of Sendai virus phosphoprotein.,Tarbouriech N, Curran J, Ruigrok RW, Burmeister WP Nat Struct Biol. 2000 Sep;7(9):777-81. PMID:10966649<ref>PMID:10966649</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The line below this paragraph, {{ABSTRACT_PUBMED_10966649}}, adds the Publication Abstract to the page
<div class="pdbe-citations 1ezj" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 10966649 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_10966649}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
1EZJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sendai_virus Sendai virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZJ OCA].
[[Category: Burmeister WP]]
 
[[Category: Curran J]]
==Reference==
[[Category: Ruigrok RWH]]
Tetrameric coiled coil domain of Sendai virus phosphoprotein., Tarbouriech N, Curran J, Ruigrok RW, Burmeister WP, Nat Struct Biol. 2000 Sep;7(9):777-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10966649 10966649]
[[Category: Tarbouriech N]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Sendai virus]]
[[Category: Single protein]]
[[Category: Burmeister, W P.]]
[[Category: Curran, J.]]
[[Category: Ruigrok, R W.H.]]
[[Category: Tarbouriech, N.]]
[[Category: Four stranded coiled coil]]
[[Category: Sendai virus]]
[[Category: Tetramer]]
[[Category: Viral polymerase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 02:15:23 2008''

Latest revision as of 05:52, 13 August 2026

CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS

1ezj, resolution 1.90Å

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