1f1z: Difference between revisions

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{{Seed}}
[[Image:1f1z.png|left|200px]]


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==TNSA, a catalytic component of the TN7 transposition system==
The line below this paragraph, containing "STRUCTURE_1f1z", creates the "Structure Box" on the page.
<StructureSection load='1f1z' size='340' side='right'caption='[[1f1z]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1f1z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F1Z FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1f1z| PDB=1f1z |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f1z OCA], [https://pdbe.org/1f1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f1z RCSB], [https://www.ebi.ac.uk/pdbsum/1f1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f1z ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TNSA_ECOLX TNSA_ECOLX] Required for Tn7 transposition. Forms the transposase, together with TnsB. TnsA executes the 5'-DNA strand breakage reaction. TnsABC and TnsD promote high-frequency insertion of Tn7 into a specific target site known as ATT-Tn7 whereas TnsABC and TnsD promote low-frequency insertion into many different sites.<ref>PMID:8947057</ref> <ref>PMID:10704304</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f1/1f1z_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f1z ConSurf].
<div style="clear:both"></div>


===TNSA, a catalytic component of the TN7 transposition system===
==See Also==
 
*[[Transposase 3D structures|Transposase 3D structures]]
 
== References ==
<!--
<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 10911996 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_10911996}}
 
==About this Structure==
1F1Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1Z OCA].
 
==Reference==
Unexpected structural diversity in DNA recombination: the restriction endonuclease connection., Hickman AB, Li Y, Mathew SV, May EW, Craig NL, Dyda F, Mol Cell. 2000 Jun;5(6):1025-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10911996 10911996]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Craig, N L.]]
[[Category: Craig NL]]
[[Category: Dyda, F.]]
[[Category: Dyda F]]
[[Category: Hickman, A B.]]
[[Category: Hickman AB]]
[[Category: Li, Y.]]
[[Category: Li Y]]
[[Category: Mathew, S V.]]
[[Category: Mathew SV]]
[[Category: May, E W.]]
[[Category: May EW]]
[[Category: Restriction endonuclease fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 02:21:12 2008''

Latest revision as of 07:09, 7 February 2024

TNSA, a catalytic component of the TN7 transposition system

1f1z, resolution 2.40Å

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