1f6y: Difference between revisions

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{{Seed}}
[[Image:1f6y.png|left|200px]]


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==MAD CRYSTAL STRUCTURE ANALYSIS OF METHYLTETRAHYDROFOLATE: CORRINOID/IRON-SULFUR PROTEIN METHYLTRANSFERASE (METR)==
The line below this paragraph, containing "STRUCTURE_1f6y", creates the "Structure Box" on the page.
<StructureSection load='1f6y' size='340' side='right'caption='[[1f6y]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1f6y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moorella_thermoacetica_ATCC_39073 Moorella thermoacetica ATCC 39073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F6Y FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f6y OCA], [https://pdbe.org/1f6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f6y RCSB], [https://www.ebi.ac.uk/pdbsum/1f6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f6y ProSAT]</span></td></tr>
{{STRUCTURE_1f6y|  PDB=1f6y  |  SCENE=  }}
</table>
 
== Function ==
===MAD CRYSTAL STRUCTURE ANALYSIS OF METHYLTETRAHYDROFOLATE: CORRINOID/IRON-SULFUR PROTEIN METHYLTRANSFERASE (METR)===
[https://www.uniprot.org/uniprot/ACSE_MOOTH ACSE_MOOTH] Methyltransferase that mediates the transfer of a N5-methyl group of (6S)-methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein in the anaerobic acetyl-CoA pathway (Wood-Ljungdahl pathway) of carbon monoxide and carbon dioxide fixation.<ref>PMID:17172470</ref> <ref>PMID:22419154</ref> <ref>PMID:7928975</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_10997901}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 10997901 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/1f6y_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_10997901}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f6y ConSurf].
1F6Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Moorella_thermoacetica Moorella thermoacetica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F6Y OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
Crystal structure of a methyltetrahydrofolate- and corrinoid-dependent methyltransferase., Doukov T, Seravalli J, Stezowski JJ, Ragsdale SW, Structure. 2000 Aug 15;8(8):817-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10997901 10997901]
__TOC__
[[Category: Moorella thermoacetica]]
</StructureSection>
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Doukov, T I.]]
[[Category: Moorella thermoacetica ATCC 39073]]
[[Category: Ragsdale, S W.]]
[[Category: Doukov TI]]
[[Category: Seravalli, J.]]
[[Category: Ragsdale SW]]
[[Category: Stezowski, J J.]]
[[Category: Seravalli J]]
[[Category: Carbon dioxide fixation]]
[[Category: Stezowski JJ]]
[[Category: Cobalamin]]
[[Category: Homodimer]]
[[Category: Methyltatrahydrofolate]]
[[Category: Methyltransferase]]
[[Category: One-carbon metabolism]]
[[Category: Tim barrel]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 02:48:11 2008''

Latest revision as of 07:11, 7 February 2024

MAD CRYSTAL STRUCTURE ANALYSIS OF METHYLTETRAHYDROFOLATE: CORRINOID/IRON-SULFUR PROTEIN METHYLTRANSFERASE (METR)

1f6y, resolution 2.20Å

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