1fbu: Difference between revisions

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{{Seed}}
[[Image:1fbu.png|left|200px]]


<!--
==HEAT SHOCK TRANSCRIPTION FACTOR DNA BINDING DOMAIN==
The line below this paragraph, containing "STRUCTURE_1fbu", creates the "Structure Box" on the page.
<StructureSection load='1fbu' size='340' side='right'caption='[[1fbu]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1fbu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FBU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fbu OCA], [https://pdbe.org/1fbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fbu RCSB], [https://www.ebi.ac.uk/pdbsum/1fbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fbu ProSAT]</span></td></tr>
{{STRUCTURE_1fbu| PDB=1fbu |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/HSF_KLULA HSF_KLULA] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. Also required for growth at normal temperatures.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/1fbu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fbu ConSurf].
<div style="clear:both"></div>


===HEAT SHOCK TRANSCRIPTION FACTOR DNA BINDING DOMAIN===
==See Also==
 
*[[Heat shock factor|Heat shock factor]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11305238}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11305238 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11305238}}
 
==About this Structure==
1FBU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FBU OCA].
 
==Reference==
Proline in alpha-helical kink is required for folding kinetics but not for kinked structure, function, or stability of heat shock transcription factor., Hardy JA, Nelson HC, Protein Sci. 2000 Nov;9(11):2128-41. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11305238 11305238]
[[Category: Kluyveromyces lactis]]
[[Category: Kluyveromyces lactis]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hardy, J A.]]
[[Category: Hardy JA]]
[[Category: Nelson, H C.M.]]
[[Category: Nelson HCM]]
[[Category: Helical bulge]]
[[Category: Helical kink]]
[[Category: Helix-turn-helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 03:00:51 2008''
Retrieved from "https://proteopedia.org/1fbu"