1fup: Difference between revisions

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{{Seed}}
[[Image:1fup.png|left|200px]]


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==FUMARASE WITH BOUND PYROMELLITIC ACID==
The line below this paragraph, containing "STRUCTURE_1fup", creates the "Structure Box" on the page.
<StructureSection load='1fup' size='340' side='right'caption='[[1fup]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1fup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FUP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=PMA:PYROMELLITIC+ACID'>PMA</scene></td></tr>
{{STRUCTURE_1fup|  PDB=1fup |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fup OCA], [https://pdbe.org/1fup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fup RCSB], [https://www.ebi.ac.uk/pdbsum/1fup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fup ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FUMC_ECOLI FUMC_ECOLI] Catalyzes the reversible addition of water to fumarate to give L-malate.<ref>PMID:1917897</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fu/1fup_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fup ConSurf].
<div style="clear:both"></div>


===FUMARASE WITH BOUND PYROMELLITIC ACID===
==See Also==
 
*[[Fumarase|Fumarase]]
 
== References ==
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<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_8909293}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 8909293 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_8909293}}
 
==About this Structure==
1FUP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FUP OCA].
 
==Reference==
Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli., Weaver T, Banaszak L, Biochemistry. 1996 Nov 5;35(44):13955-65. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8909293 8909293]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Fumarate hydratase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Banaszak L]]
[[Category: Banaszak, L.]]
[[Category: Weaver T]]
[[Category: Weaver, T.]]
[[Category: Lyase]]
[[Category: Tricarboxylic acid cycle]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 03:58:36 2008''