1fz9: Difference between revisions

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{{Seed}}
[[Image:1fz9.png|left|200px]]


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==Methane monooxygenase hydroxylase, form II cocrystallized with iodoethane==
The line below this paragraph, containing "STRUCTURE_1fz9", creates the "Structure Box" on the page.
<StructureSection load='1fz9' size='340' side='right'caption='[[1fz9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1fz9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FZ9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ETI:IODOETHANE'>ETI</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
{{STRUCTURE_1fz9| PDB=1fz9 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fz9 OCA], [https://pdbe.org/1fz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fz9 RCSB], [https://www.ebi.ac.uk/pdbsum/1fz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fz9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MEMA_METCA MEMA_METCA] Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fz/1fz9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fz9 ConSurf].
<div style="clear:both"></div>


===METHANE MONOOXYGENASE HYDROXYLASE, FORM II COCRYSTALLIZED WITH IODOETHANE===
==See Also==
 
*[[Methane monooxygenase 3D structures|Methane monooxygenase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11297413}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 11297413 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11297413}}
 
==About this Structure==
1FZ9 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZ9 OCA].
 
==Reference==
Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase., Whittington DA, Rosenzweig AC, Frederick CA, Lippard SJ, Biochemistry. 2001 Mar 27;40(12):3476-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11297413 11297413]
[[Category: Methane monooxygenase]]
[[Category: Methylococcus capsulatus]]
[[Category: Methylococcus capsulatus]]
[[Category: Protein complex]]
[[Category: Frederick CA]]
[[Category: Frederick, C A.]]
[[Category: Lippard SJ]]
[[Category: Lippard, S J.]]
[[Category: Rosenzweig AC]]
[[Category: Rosenzweig, A C.]]
[[Category: Whittington DA]]
[[Category: Whittington, D A.]]
[[Category: Dinuclear iron center]]
[[Category: Monooxygenase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 04:09:47 2008''
Retrieved from "https://proteopedia.org/1fz9"