1g5n: Difference between revisions

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{{Seed}}
[[Image:1g5n.png|left|200px]]


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==ANNEXIN V COMPLEX WITH HEPARIN OLIGOSACCHARIDES==
The line below this paragraph, containing "STRUCTURE_1g5n", creates the "Structure Box" on the page.
<StructureSection load='1g5n' size='340' side='right'caption='[[1g5n]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1g5n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G5N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G5N FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene>, <scene name='pdbligand=UAP:4-DEOXY-2-O-SULFO-ALPHA-L-THREO-HEX-4-ENOPYRANURONIC+ACID'>UAP</scene></td></tr>
{{STRUCTURE_1g5n| PDB=1g5n |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g5n OCA], [https://pdbe.org/1g5n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g5n RCSB], [https://www.ebi.ac.uk/pdbsum/1g5n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g5n ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ANXA5_RAT ANXA5_RAT] This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g5/1g5n_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g5n ConSurf].
<div style="clear:both"></div>


===ANNEXIN V COMPLEX WITH HEPARIN OLIGOSACCHARIDES===
==See Also==
 
*[[Annexin 3D structures|Annexin 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11342135}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 11342135 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11342135}}
 
==About this Structure==
1G5N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G5N OCA].
 
==Reference==
Annexin V--heparin oligosaccharide complex suggests heparan sulfate--mediated assembly on cell surfaces., Capila I, Hernaiz MJ, Mo YD, Mealy TR, Campos B, Dedman JR, Linhardt RJ, Seaton BA, Structure. 2001 Jan 10;9(1):57-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11342135 11342135]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Campos B]]
[[Category: Campos, B.]]
[[Category: Capila I]]
[[Category: Capila, I.]]
[[Category: Dedman JR]]
[[Category: Dedman, J R.]]
[[Category: Heraiz MJ]]
[[Category: Heraiz, M J.]]
[[Category: Linhardt RJ]]
[[Category: Linhardt, R J.]]
[[Category: Mealy TR]]
[[Category: Mealy, T R.]]
[[Category: Mo YD]]
[[Category: Mo, Y D.]]
[[Category: Seaton BA]]
[[Category: Seaton, B A.]]
[[Category: Calcium]]
[[Category: Helix-bundle]]
[[Category: Heparan sulfate]]
[[Category: Heparin]]
[[Category: Membrane binding]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 04:28:43 2008''