1g60: Difference between revisions

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{{Seed}}
[[Image:1g60.png|left|200px]]


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==Crystal Structure of Methyltransferase MboIIa (Moraxella bovis)==
The line below this paragraph, containing "STRUCTURE_1g60", creates the "Structure Box" on the page.
<StructureSection load='1g60' size='340' side='right'caption='[[1g60]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1g60]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moraxella_bovis Moraxella bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G60 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
{{STRUCTURE_1g60| PDB=1g60 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g60 OCA], [https://pdbe.org/1g60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g60 RCSB], [https://www.ebi.ac.uk/pdbsum/1g60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g60 ProSAT], [https://www.topsan.org/Proteins/MCSG/1g60 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTM2_MORBO MTM2_MORBO] This methylase recognizes the double-stranded sequence GAAGA, causes specific methylation on A-5, and protects the DNA from cleavage by the MboII endonuclease. It is not known if the cytosine of the complementary sequence TCTTC is also methylated by this enzyme.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/1g60_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g60 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of Methyltransferase MboIIa (Moraxella bovis)===
==See Also==
 
*[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12954781}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 12954781 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12954781}}
 
==About this Structure==
1G60 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Moraxella_bovis Moraxella bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G60 OCA].
 
==Reference==
Crystal structure of MboIIA methyltransferase., Osipiuk J, Walsh MA, Joachimiak A, Nucleic Acids Res. 2003 Sep 15;31(18):5440-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12954781 12954781]
[[Category: Moraxella bovis]]
[[Category: Moraxella bovis]]
[[Category: Single protein]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A.]]
[[Category: Osipiuk J]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Walsh MA]]
[[Category: Osipiuk, J.]]
[[Category: Walsh, M A.]]
[[Category: Dna methylation]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Moraxella bovi]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: S-adenosylmethionine]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 04:30:44 2008''

Latest revision as of 07:23, 7 February 2024

Crystal Structure of Methyltransferase MboIIa (Moraxella bovis)

1g60, resolution 1.74Å

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