1g7v: Difference between revisions

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{{Seed}}
[[Image:1g7v.png|left|200px]]


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==CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEXES WITH THE MECHANISM-BASED INHIBITOR==
The line below this paragraph, containing "STRUCTURE_1g7v", creates the "Structure Box" on the page.
<StructureSection load='1g7v' size='340' side='right'caption='[[1g7v]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1g7v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G7V FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PAI:{[(2,2-DIHYDROXY-ETHYL)-(2,3,4,5-TETRAHYDROXY-6-PHOSPHONOOXY-HEXYL)-AMINO]-METHYL}-PHOSPHONIC+ACID'>PAI</scene></td></tr>
{{STRUCTURE_1g7v| PDB=1g7v |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g7v OCA], [https://pdbe.org/1g7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g7v RCSB], [https://www.ebi.ac.uk/pdbsum/1g7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g7v ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KDSA_ECOLI KDSA_ECOLI] Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.[HAMAP-Rule:MF_00056]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g7/1g7v_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g7v ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEXES WITH THE MECHANISM-BASED INHIBITOR===
==See Also==
 
*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11371194}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11371194 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11371194}}
 
==About this Structure==
1G7V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G7V OCA].
 
==Reference==
Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanism-based inhibitor., Asojo O, Friedman J, Adir N, Belakhov V, Shoham Y, Baasov T, Biochemistry. 2001 May 29;40(21):6326-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11371194 11371194]
[[Category: 3-deoxy-8-phosphooctulonate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Adir, N.]]
[[Category: Adir N]]
[[Category: Asojo, O A.]]
[[Category: Asojo OA]]
[[Category: Baasov, T.]]
[[Category: Baasov T]]
[[Category: Belakhov, V.]]
[[Category: Belakhov V]]
[[Category: Friedman, J M.]]
[[Category: Friedman JM]]
[[Category: Shoham, Y.]]
[[Category: Shoham Y]]
[[Category: Beta-alpha-barrel]]
[[Category: Lipopolysaccharide]]
[[Category: Lyase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 04:51:07 2008''
Retrieved from "https://proteopedia.org/1g7v"