1gau: Difference between revisions

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{{Seed}}
[[Image:1gau.png|left|200px]]


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==SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR==
The line below this paragraph, containing "STRUCTURE_1gau", creates the "Structure Box" on the page.
<StructureSection load='1gau' size='340' side='right'caption='[[1gau]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1gau]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GAU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gau OCA], [https://pdbe.org/1gau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gau RCSB], [https://www.ebi.ac.uk/pdbsum/1gau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gau ProSAT]</span></td></tr>
{{STRUCTURE_1gau|  PDB=1gau  |  SCENE=  }}
</table>
 
== Function ==
===SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR===
[https://www.uniprot.org/uniprot/GATA1_CHICK GATA1_CHICK] Transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_1567844}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 1567844 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/1gau_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_1567844}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gau ConSurf].
Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GAU OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
High-resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1., Omichinski JG, Clore GM, Robien M, Sakaguchi K, Appella E, Gronenborn AM, Biochemistry. 1992 Apr 28;31(16):3907-17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1567844 1567844]
[[Category: Gallus gallus]]
[[Category: Clore, G M.]]
[[Category: Large Structures]]
[[Category: Gronenborn, A M.]]
[[Category: Clore GM]]
[[Category: Omichinski, J G.]]
[[Category: Gronenborn AM]]
[[Category: Transcription/dna]]
[[Category: Omichinski JG]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 05:00:27 2008''
Retrieved from "https://proteopedia.org/1gau"