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{{Seed}}
[[Image:1grl.png|left|200px]]


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==THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS==
The line below this paragraph, containing "STRUCTURE_1grl", creates the "Structure Box" on the page.
<StructureSection load='1grl' size='340' side='right'caption='[[1grl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1grl]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GRL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1grl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1grl OCA], [https://pdbe.org/1grl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1grl RCSB], [https://www.ebi.ac.uk/pdbsum/1grl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1grl ProSAT]</span></td></tr>
{{STRUCTURE_1grl| PDB=1grl |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600]  Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gr/1grl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1grl ConSurf].
<div style="clear:both"></div>


===THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS===
==See Also==
 
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_7935790}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 7935790 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_7935790}}
 
==About this Structure==
1GRL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GRL OCA].
 
==Reference==
The crystal structure of the bacterial chaperonin GroEL at 2.8 A., Braig K, Otwinowski Z, Hegde R, Boisvert DC, Joachimiak A, Horwich AL, Sigler PB, Nature. 1994 Oct 13;371(6498):578-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7935790 7935790]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Boisvert, D C.]]
[[Category: Boisvert DC]]
[[Category: Braig, K.]]
[[Category: Braig K]]
[[Category: Hegde, R.]]
[[Category: Hegde R]]
[[Category: Horwich, A L.]]
[[Category: Horwich AL]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak A]]
[[Category: Otwinowski, Z.]]
[[Category: Otwinowski Z]]
[[Category: Sigler, P B.]]
[[Category: Sigler PB]]
[[Category: Chaperonin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 05:57:29 2008''

Latest revision as of 07:26, 7 February 2024

THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS

1grl, resolution 2.80Å

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