1fz6: Difference between revisions
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New page: left|200px<br /><applet load="1fz6" size="450" color="white" frame="true" align="right" spinBox="true" caption="1fz6, resolution 2.05Å" /> '''METHANE MONOOXYGENAS... |
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== | ==METHANE MONOOXYGENASE HYDROXYLASE, FORM II SOAKED IN 1 M METHANOL== | ||
<StructureSection load='1fz6' size='340' side='right'caption='[[1fz6]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
[[Category: | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1fz6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FZ6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fz6 OCA], [https://pdbe.org/1fz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fz6 RCSB], [https://www.ebi.ac.uk/pdbsum/1fz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fz6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MEMG_METCA MEMG_METCA] Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fz/1fz6_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fz6 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Methane monooxygenase 3D structures|Methane monooxygenase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Methylococcus capsulatus]] | [[Category: Methylococcus capsulatus]] | ||
[[Category: Lippard SJ]] | |||
[[Category: Lippard | [[Category: Sazinsky MH]] | ||
[[Category: Sazinsky | [[Category: Whittington DA]] | ||
[[Category: Whittington | |||
Latest revision as of 07:20, 7 February 2024
METHANE MONOOXYGENASE HYDROXYLASE, FORM II SOAKED IN 1 M METHANOL
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