1gz3: Difference between revisions

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[[Image:1gz3.png|left|200px]]


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==Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate==
The line below this paragraph, containing "STRUCTURE_1gz3", creates the "Structure Box" on the page.
<StructureSection load='1gz3' size='340' side='right'caption='[[1gz3]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1gz3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GZ3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=FUM:FUMARIC+ACID'>FUM</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
{{STRUCTURE_1gz3|  PDB=1gz3  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gz3 OCA], [https://pdbe.org/1gz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gz3 RCSB], [https://www.ebi.ac.uk/pdbsum/1gz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gz3 ProSAT]</span></td></tr>
 
</table>
===MOLECULAR MECHANISM FOR THE REGULATION OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME BY ATP AND FUMARATE===
== Function ==
 
[https://www.uniprot.org/uniprot/MAOM_HUMAN MAOM_HUMAN]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gz/1gz3_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12121650}}
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==About this Structure==
  </jmolCheckbox>
1GZ3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GZ3 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gz3 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate., Yang Z, Lanks CW, Tong L, Structure. 2002 Jul;10(7):951-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12121650 12121650]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Lanks, C W.]]
[[Category: Lanks CW]]
[[Category: Liang, T.]]
[[Category: Tong L]]
[[Category: Yang, Z.]]
[[Category: Yang Z]]
[[Category: Allosteric regulation]]
[[Category: Energy metabolism]]
[[Category: Kinetic]]
[[Category: Mitochondrion.]]
[[Category: Nad]]
[[Category: Oxidoreductase]]
[[Category: Protein structure]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 06:20:51 2008''

Latest revision as of 06:29, 1 May 2024

Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate

1gz3, resolution 2.30Å

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