1ho1: Difference between revisions

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{{Seed}}
[[Image:1ho1.png|left|200px]]


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==CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE==
The line below this paragraph, containing "STRUCTURE_1ho1", creates the "Structure Box" on the page.
<StructureSection load='1ho1' size='340' side='right'caption='[[1ho1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ho1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HO1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HO1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ho1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ho1 OCA], [https://pdbe.org/1ho1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ho1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ho1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ho1 ProSAT]</span></td></tr>
{{STRUCTURE_1ho1|  PDB=1ho1  |  SCENE=  }}
</table>
 
== Function ==
===CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE===
[https://www.uniprot.org/uniprot/PDXJ_ECOLI PDXJ_ECOLI] Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.<ref>PMID:10225425</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_11286891}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 11286891 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/1ho1_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_11286891}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ho1 ConSurf].
1HO1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HO1 OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
Structural basis for the function of pyridoxine 5'-phosphate synthase., Franco MG, Laber B, Huber R, Clausen T, Structure. 2001 Mar 7;9(3):245-53. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11286891 11286891]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Clausen, T.]]
[[Category: Clausen T]]
[[Category: Garrido-Franco, M.]]
[[Category: Garrido-Franco M]]
[[Category: Huber, R.]]
[[Category: Huber R]]
[[Category: Laber, B.]]
[[Category: Laber B]]
[[Category: Tim barrel]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 08:27:24 2008''
Retrieved from "https://proteopedia.org/1ho1"