1hon: Difference between revisions

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{{Seed}}
[[Image:1hon.png|left|200px]]


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==STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREE CELSIUS==
The line below this paragraph, containing "STRUCTURE_1hon", creates the "Structure Box" on the page.
<StructureSection load='1hon' size='340' side='right'caption='[[1hon]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1hon]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HON FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNH:AMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNH</scene></td></tr>
{{STRUCTURE_1hon| PDB=1hon |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hon OCA], [https://pdbe.org/1hon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hon RCSB], [https://www.ebi.ac.uk/pdbsum/1hon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hon ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PURA_ECOLI PURA_ECOLI] Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).[HAMAP-Rule:MF_00011]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/1hon_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hon ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREE CELSIUS===
==See Also==
 
*[[Adenylosuccinate synthetase 3D structures|Adenylosuccinate synthetase 3D structures]]
 
__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_8663109}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 8663109 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8663109}}
 
==About this Structure==
1HON is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HON OCA].
 
==Reference==
Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli., Poland BW, Hou Z, Bruns C, Fromm HJ, Honzatko RB, J Biol Chem. 1996 Jun 28;271(26):15407-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8663109 8663109]
[[Category: Adenylosuccinate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bruns, C.]]
[[Category: Bruns C]]
[[Category: Fromm, H J.]]
[[Category: Fromm HJ]]
[[Category: Honzatko, R B.]]
[[Category: Honzatko RB]]
[[Category: Hou, Z.]]
[[Category: Hou Z]]
[[Category: Poland, B W.]]
[[Category: Poland BW]]
[[Category: Gtp-binding enzyme]]
[[Category: Ligase]]
[[Category: Purine nucleotide biosynthesis]]
[[Category: Synthetase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 08:28:21 2008''