1hy1: Difference between revisions

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{{Seed}}
[[Image:1hy1.png|left|200px]]


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==CRYSTAL STRUCTURE OF WILD TYPE DUCK DELTA 2 CRYSTALLIN (EYE LENS PROTEIN)==
The line below this paragraph, containing "STRUCTURE_1hy1", creates the "Structure Box" on the page.
<StructureSection load='1hy1' size='340' side='right'caption='[[1hy1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1hy1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anas_platyrhynchos Anas platyrhynchos]. The July 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Crystallins''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_7 10.2210/rcsb_pdb/mom_2010_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HY1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hy1 OCA], [https://pdbe.org/1hy1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hy1 RCSB], [https://www.ebi.ac.uk/pdbsum/1hy1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hy1 ProSAT]</span></td></tr>
{{STRUCTURE_1hy1| PDB=1hy1 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARLY2_ANAPL ARLY2_ANAPL] Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles. This protein also functions as an enzymatically active argininosuccinate lyase.<ref>PMID:10029536</ref> <ref>PMID:11698398</ref> <ref>PMID:15320872</ref> <ref>PMID:9369472</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hy/1hy1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hy1 ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF WILD TYPE DUCK DELTA 2 CRYSTALLIN (EYE LENS PROTEIN)===
==See Also==
 
*[[Crystallin 3D structures|Crystallin 3D structures]]
 
== References ==
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{{ABSTRACT_PUBMED_11258884}}
 
==About this Structure==
1HY1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Anas_platyrhynchos Anas platyrhynchos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HY1 OCA].
 
==Reference==
Structural studies of duck delta 1 and delta 2 crystallin suggest conformational changes occur during catalysis., Sampaleanu LM, Vallee F, Slingsby C, Howell PL, Biochemistry. 2001 Mar 6;40(9):2732-42. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11258884 11258884]
[[Category: Anas platyrhynchos]]
[[Category: Anas platyrhynchos]]
[[Category: Argininosuccinate lyase]]
[[Category: Crystallins]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Howell, P L.]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Sampaleanu, L M.]]
[[Category: Howell PL]]
[[Category: Slingsby, C.]]
[[Category: Sampaleanu LM]]
[[Category: Vallee, F.]]
[[Category: Slingsby C]]
[[Category: Argininosuccinate lyase]]
[[Category: Vallee F]]
[[Category: Delta 2 crystallin]]
[[Category: Eye lens protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 10:06:36 2008''
Retrieved from "https://proteopedia.org/1hy1"