1ib6: Difference between revisions

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{{Seed}}
[[Image:1ib6.png|left|200px]]


<!--
==CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE==
The line below this paragraph, containing "STRUCTURE_1ib6", creates the "Structure Box" on the page.
<StructureSection load='1ib6' size='340' side='right'caption='[[1ib6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ib6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IB6 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1ib6|  PDB=1ib6 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ib6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ib6 OCA], [https://pdbe.org/1ib6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ib6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ib6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ib6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ib/1ib6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ib6 ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE===
==See Also==
 
*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11389141}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11389141 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11389141}}
 
==About this Structure==
1IB6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IB6 OCA].
 
==Reference==
Structural analyses of a malate dehydrogenase with a variable active site., Bell JK, Yennawar HP, Wright SK, Thompson JR, Viola RE, Banaszak LJ, J Biol Chem. 2001 Aug 17;276(33):31156-62. Epub 2001 Jun 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11389141 11389141]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Malate dehydrogenase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Banaszak LJ]]
[[Category: Banaszak, L J.]]
[[Category: Bell JK]]
[[Category: Bell, J K.]]
[[Category: Thompson JR]]
[[Category: Thompson, J R.]]
[[Category: Viola RE]]
[[Category: Viola, R E.]]
[[Category: Wright SK]]
[[Category: Wright, S K.]]
[[Category: Yennawar HP]]
[[Category: Yennawar, H P.]]
[[Category: Dehydrogenase]]
[[Category: Malate dehydrogenase]]
[[Category: Oxidoreductase]]
[[Category: Substrate specificity]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 10:41:55 2008''

Latest revision as of 07:33, 7 February 2024

CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE

1ib6, resolution 2.10Å

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