1ifa: Difference between revisions

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{{Seed}}
[[Image:1ifa.png|left|200px]]


<!--
==THREE-DIMENSIONAL CRYSTAL STRUCTURE OF RECOMBINANT MURINE INTERFERON-BETA==
The line below this paragraph, containing "STRUCTURE_1ifa", creates the "Structure Box" on the page.
<StructureSection load='1ifa' size='340' side='right'caption='[[1ifa]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ifa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IFA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASN:ASPARAGINE'>ASN</scene></td></tr>
{{STRUCTURE_1ifa| PDB=1ifa |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ifa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ifa OCA], [https://pdbe.org/1ifa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ifa RCSB], [https://www.ebi.ac.uk/pdbsum/1ifa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ifa ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IFNB_MOUSE IFNB_MOUSE] Has antiviral, antibacterial and anticancer activities.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/1ifa_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ifa ConSurf].
<div style="clear:both"></div>


===THREE-DIMENSIONAL CRYSTAL STRUCTURE OF RECOMBINANT MURINE INTERFERON-BETA===
==See Also==
 
*[[Interferon 3D structures|Interferon 3D structures]]
 
*[[Multiple sclerosis|Multiple sclerosis]]
<!--
__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_1505514}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 1505514 is the PubMed ID number.
[[Category: Large Structures]]
-->
{{ABSTRACT_PUBMED_1505514}}
 
==About this Structure==
1IFA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IFA OCA].
 
==Reference==
Three-dimensional crystal structure of recombinant murine interferon-beta., Senda T, Shimazu T, Matsuda S, Kawano G, Shimizu H, Nakamura KT, Mitsui Y, EMBO J. 1992 Sep;11(9):3193-201. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1505514 1505514]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Kawano G]]
[[Category: Kawano, G.]]
[[Category: Matsuda S]]
[[Category: Matsuda, S.]]
[[Category: Mitsui Y]]
[[Category: Mitsui, Y.]]
[[Category: Nakamura KT]]
[[Category: Nakamura, K T.]]
[[Category: Senda T]]
[[Category: Senda, T.]]
[[Category: Shimizu H]]
[[Category: Shimizu, H.]]
[[Category: Glycoprotein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 10:52:55 2008''

Latest revision as of 07:34, 7 February 2024

THREE-DIMENSIONAL CRYSTAL STRUCTURE OF RECOMBINANT MURINE INTERFERON-BETA

1ifa, resolution 2.60Å

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