1ii3: Difference between revisions

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{{Seed}}
[[Image:1ii3.png|left|200px]]


<!--
==Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L==
The line below this paragraph, containing "STRUCTURE_1ii3", creates the "Structure Box" on the page.
<StructureSection load='1ii3' size='340' side='right'caption='[[1ii3]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ii3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1II3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1II3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ii3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ii3 OCA], [https://pdbe.org/1ii3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ii3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ii3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ii3 ProSAT]</span></td></tr>
{{STRUCTURE_1ii3| PDB=1ii3 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/1ii3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ii3 ConSurf].
<div style="clear:both"></div>


===Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L===
==See Also==
 
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_15228960}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 15228960 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_15228960}}
 
==About this Structure==
1II3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1II3 OCA].
 
==Reference==
Proteins with simplified hydrophobic cores compared to other packing mutants., Chen J, Lu Z, Sakon J, Stites WE, Biophys Chem. 2004 Aug 1;110(3):239-48. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15228960 15228960]
[[Category: Micrococcal nuclease]]
[[Category: Single protein]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Chen, J.]]
[[Category: Chen J]]
[[Category: Lu, Z.]]
[[Category: Lu Z]]
[[Category: Sakon, J.]]
[[Category: Sakon J]]
[[Category: Stites, W E.]]
[[Category: Stites WE]]
[[Category: Hydrolase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 12:14:40 2008''

Latest revision as of 07:35, 7 February 2024

Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L

1ii3, resolution 1.72Å

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