1ijv: Difference between revisions

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{{Seed}}
[[Image:1ijv.png|left|200px]]


<!--
==HUMAN BETA-DEFENSIN-1==
The line below this paragraph, containing "STRUCTURE_1ijv", creates the "Structure Box" on the page.
<StructureSection load='1ijv' size='340' side='right'caption='[[1ijv]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ijv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IJV FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1ijv| PDB=1ijv |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ijv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ijv OCA], [https://pdbe.org/1ijv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ijv RCSB], [https://www.ebi.ac.uk/pdbsum/1ijv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ijv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEFB1_HUMAN DEFB1_HUMAN] Has bactericidal activity (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ij/1ijv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ijv ConSurf].
<div style="clear:both"></div>


===HUMAN BETA-DEFENSIN-1===
==See Also==
 
*[[Defensin 3D structures|Defensin 3D structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11486002}}, adds the Publication Abstract to the page
[[Category: Homo sapiens]]
(as it appears on PubMed at http://www.pubmed.gov), where 11486002 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Hoover DM]]
{{ABSTRACT_PUBMED_11486002}}
[[Category: Lubkowski J]]
 
==About this Structure==
1IJV is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJV OCA].
 
==Reference==
The structure of human beta-defensin-1: new insights into structural properties of beta-defensins., Hoover DM, Chertov O, Lubkowski J, J Biol Chem. 2001 Oct 19;276(42):39021-6. Epub 2001 Aug 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11486002 11486002]
[[Category: Single protein]]
[[Category: Hoover, D M.]]
[[Category: Lubkowski, J.]]
[[Category: Beta-defensin]]
[[Category: Defensin]]
[[Category: Human beta-defensin-1]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 12:23:54 2008''
Retrieved from "https://proteopedia.org/1ijv"