1ik4: Difference between revisions

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{{Seed}}
[[Image:1ik4.png|left|200px]]


<!--
==X-ray Structure of Methylglyoxal Synthase from E. coli Complexed with Phosphoglycolohydroxamic Acid==
The line below this paragraph, containing "STRUCTURE_1ik4", creates the "Structure Box" on the page.
<StructureSection load='1ik4' size='340' side='right'caption='[[1ik4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ik4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IK4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGH:PHOSPHOGLYCOLOHYDROXAMIC+ACID'>PGH</scene></td></tr>
{{STRUCTURE_1ik4|  PDB=1ik4  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ik4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ik4 OCA], [https://pdbe.org/1ik4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ik4 RCSB], [https://www.ebi.ac.uk/pdbsum/1ik4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ik4 ProSAT]</span></td></tr>
 
</table>
===X-ray Structure of Methylglyoxal Synthase from E. coli Complexed with Phosphoglycolohydroxamic Acid===
== Function ==
 
[https://www.uniprot.org/uniprot/MGSA_ECOLI MGSA_ECOLI]
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_11389594}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 11389594 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ik/1ik4_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_11389594}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1IK4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IK4 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ik4 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Mechanistic implications of methylglyoxal synthase complexed with phosphoglycolohydroxamic acid as observed by X-ray crystallography and NMR spectroscopy., Marks GT, Harris TK, Massiah MA, Mildvan AS, Harrison DH, Biochemistry. 2001 Jun 12;40(23):6805-18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11389594 11389594]
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Methylglyoxal synthase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Harris TK]]
[[Category: Harris, T K.]]
[[Category: Harrison DHT]]
[[Category: Harrison, D H.T.]]
[[Category: Marks GT]]
[[Category: Marks, G T.]]
[[Category: Massiah MA]]
[[Category: Massiah, M A.]]
[[Category: Mildvan AS]]
[[Category: Mildvan, A S.]]
[[Category: Glycolytic bypass]]
[[Category: Lyase]]
[[Category: Methylglyoxal]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 13:20:39 2008''

Latest revision as of 07:36, 7 February 2024

X-ray Structure of Methylglyoxal Synthase from E. coli Complexed with Phosphoglycolohydroxamic Acid

1ik4, resolution 2.00Å

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