1iva: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(10 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1iva.png|left|200px]]


<!--
==STRUCTURE-ACTIVITY RELATIONSHIPS FOR P-TYPE CALCIUM CHANNEL SELECTIVE OMEGA-AGATOXINS==
The line below this paragraph, containing "STRUCTURE_1iva", creates the "Structure Box" on the page.
<StructureSection load='1iva' size='340' side='right'caption='[[1iva]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1iva]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agelenopsis_aperta Agelenopsis aperta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IVA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 16 models</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iva OCA], [https://pdbe.org/1iva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iva RCSB], [https://www.ebi.ac.uk/pdbsum/1iva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iva ProSAT]</span></td></tr>
{{STRUCTURE_1iva|  PDB=1iva  |  SCENE=  }}
</table>
 
== Function ==
===STRUCTURE-ACTIVITY RELATIONSHIPS FOR P-TYPE CALCIUM CHANNEL SELECTIVE OMEGA-AGATOXINS===
[https://www.uniprot.org/uniprot/TX23A_AGEAP TX23A_AGEAP] Omega-agatoxins inhibit neuronal voltage-gated calcium channels. This toxin acts by modifying the gating of the high voltage activated P-type Cav2.1/CACNA1A channel. Is a potent blocker in both insect and mammalian central neurons.<ref>PMID:11055992</ref> <ref>PMID:11522785</ref> <ref>PMID:1311418</ref> <ref>PMID:7898748</ref> <ref>PMID:8250902</ref> <ref>PMID:9120560</ref> <ref>PMID:9129813</ref>
 
== References ==
 
<references/>
==About this Structure==
__TOC__
1IVA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Agelenopsis_aperta Agelenopsis aperta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IVA OCA].  
</StructureSection>
 
==Reference==
Structure-activity relationships for P-type calcium channel-selective omega-agatoxins., Reily MD, Holub KE, Gray WR, Norris TM, Adams ME, Nat Struct Biol. 1994 Dec;1(12):853-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7773772 7773772]
[[Category: Agelenopsis aperta]]
[[Category: Agelenopsis aperta]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Holub, K E.]]
[[Category: Holub KE]]
[[Category: Reily, M D.]]
[[Category: Reily MD]]
[[Category: Neurotoxin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 14:03:54 2008''

Latest revision as of 07:18, 9 October 2024

STRUCTURE-ACTIVITY RELATIONSHIPS FOR P-TYPE CALCIUM CHANNEL SELECTIVE OMEGA-AGATOXINS

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1iva&oldid=4216949"