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New page: left|200px<br /><applet load="1gp1" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gp1, resolution 2.0Å" /> '''THE REFINED STRUCTURE...
 
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[[Image:1gp1.gif|left|200px]]<br /><applet load="1gp1" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1gp1, resolution 2.0&Aring;" />
'''THE REFINED STRUCTURE OF THE SELENOENZYME GLUTATHIONE PEROXIDASE AT 0.2-NM RESOLUTION'''<br />


==About this Structure==
==THE REFINED STRUCTURE OF THE SELENOENZYME GLUTATHIONE PEROXIDASE AT 0.2-NM RESOLUTION==
1GP1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Active as [http://en.wikipedia.org/wiki/Glutathione_peroxidase Glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.9 1.11.1.9] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GP1 OCA].  
<StructureSection load='1gp1' size='340' side='right'caption='[[1gp1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Glutathione peroxidase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1gp1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The August 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Selenocysteine Synthase''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_8 10.2210/rcsb_pdb/mom_2008_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GP1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GP1 FirstGlance]. <br>
[[Category: Epp, O.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Ladenstein, R.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SE7:2-AMINO-3-SELENINO-PROPIONIC+ACID'>SE7</scene></td></tr>
[[Category: oxidoreductase(h2o2(a))]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gp1 OCA], [https://pdbe.org/1gp1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gp1 RCSB], [https://www.ebi.ac.uk/pdbsum/1gp1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gp1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GPX1_BOVIN GPX1_BOVIN] Protects the hemoglobin in erythrocytes from oxidative breakdown.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gp/1gp1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gp1 ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 16:12:49 2007''
==See Also==
*[[Glutathione peroxidase|Glutathione peroxidase]]
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Selenocysteine Synthase]]
[[Category: Epp O]]
[[Category: Ladenstein R]]

Latest revision as of 12:43, 26 July 2023

THE REFINED STRUCTURE OF THE SELENOENZYME GLUTATHIONE PEROXIDASE AT 0.2-NM RESOLUTION

1gp1, resolution 2.00Å

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