1j4a: Difference between revisions

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{{Seed}}
[[Image:1j4a.png|left|200px]]


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==INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS==
The line below this paragraph, containing "STRUCTURE_1j4a", creates the "Structure Box" on the page.
<StructureSection load='1j4a' size='340' side='right'caption='[[1j4a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1j4a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactobacillus_delbrueckii_subsp._bulgaricus Lactobacillus delbrueckii subsp. bulgaricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J4A FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1j4a|  PDB=1j4a |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j4a OCA], [https://pdbe.org/1j4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j4a RCSB], [https://www.ebi.ac.uk/pdbsum/1j4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j4a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDHD_LACDA LDHD_LACDA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/1j4a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j4a ConSurf].
<div style="clear:both"></div>


===INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS===
==See Also==
 
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12054772}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12054772 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12054772}}
 
==About this Structure==
1J4A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_delbrueckii_subsp._bulgaricus Lactobacillus delbrueckii subsp. bulgaricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4A OCA].
 
==Reference==
Domain closure, substrate specificity and catalysis of D-lactate dehydrogenase from Lactobacillus bulgaricus., Razeto A, Kochhar S, Hottinger H, Dauter M, Wilson KS, Lamzin VS, J Mol Biol. 2002 Apr 19;318(1):109-19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12054772 12054772]
[[Category: D-lactate dehydrogenase]]
[[Category: Lactobacillus delbrueckii subsp. bulgaricus]]
[[Category: Lactobacillus delbrueckii subsp. bulgaricus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Dauter, M.]]
[[Category: Dauter M]]
[[Category: Hottinger, H.]]
[[Category: Hottinger H]]
[[Category: Kochhar, S.]]
[[Category: Kochhar S]]
[[Category: Lamzin, V S.]]
[[Category: Lamzin VS]]
[[Category: Razeto, A.]]
[[Category: Razeto A]]
[[Category: Wilson, K S.]]
[[Category: Wilson KS]]
[[Category: Nad-dependent dehydrogenase]]
[[Category: Reversible interconversion of pyruvate into d-lactate]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 14:28:46 2008''

Latest revision as of 06:03, 3 April 2024

INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS

1j4a, resolution 1.90Å

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