1jpd: Difference between revisions

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{{Seed}}
[[Image:1jpd.png|left|200px]]


<!--
==L-Ala-D/L-Glu Epimerase==
The line below this paragraph, containing "STRUCTURE_1jpd", creates the "Structure Box" on the page.
<StructureSection load='1jpd' size='340' side='right'caption='[[1jpd]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1jpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JPD FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpd OCA], [https://pdbe.org/1jpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jpd RCSB], [https://www.ebi.ac.uk/pdbsum/1jpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jpd ProSAT]</span></td></tr>
{{STRUCTURE_1jpd|  PDB=1jpd  |  SCENE=  }}
</table>
 
== Function ==
===L-Ala-D/L-Glu Epimerase===
[https://www.uniprot.org/uniprot/AEEP_ECOLI AEEP_ECOLI] Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has a role in the recycling of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of all the L-Ala-X dipeptides, except L-Ala-L-Arg, L-Ala-L-Lys and L-Ala-L-Pro. Is also active with L-Gly-L-Glu, L-Phe-L-Glu, and L-Ser-L-Glu, but not with L-Glu-L-Glu, L-Lys-L-Glu, L-Pro-L-Glu, L-Lys-L-Ala, or D-Ala-D-Ala.<ref>PMID:11747447</ref> <ref>PMID:18535144</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_11747448}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11747448 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jp/1jpd_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_11747448}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jpd ConSurf].
1JPD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPD OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis., Gulick AM, Schmidt DM, Gerlt JA, Rayment I, Biochemistry. 2001 Dec 25;40(51):15716-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11747448 11747448]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Gerlt, J A.]]
[[Category: Gerlt JA]]
[[Category: Gulick, A M.]]
[[Category: Gulick AM]]
[[Category: Rayment, I.]]
[[Category: Rayment I]]
[[Category: Schmidt, D M.Z.]]
[[Category: Schmidt DMZ]]
[[Category: Alpha/beta barrel]]
[[Category: Enolase superfamily]]
[[Category: Muconate lactonizing enzyme subgroup]]
[[Category: Structural genomic]]
 
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Retrieved from "https://proteopedia.org/1jpd"