1jye: Difference between revisions

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{{Seed}}
[[Image:1jye.png|left|200px]]


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==Structure of a Dimeric Lac Repressor with C-terminal Deletion and K84L Substitution==
The line below this paragraph, containing "STRUCTURE_1jye", creates the "Structure Box" on the page.
<StructureSection load='1jye' size='340' side='right'caption='[[1jye]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1jye]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JYE FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_1jye|  PDB=1jye |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jye OCA], [https://pdbe.org/1jye PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jye RCSB], [https://www.ebi.ac.uk/pdbsum/1jye PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jye ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jy/1jye_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jye ConSurf].
<div style="clear:both"></div>


===Structure of a Dimeric Lac Repressor with C-terminal Deletion and K84L Substitution===
==See Also==
 
*[[Lac repressor|Lac repressor]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11601849}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11601849 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11601849}}
 
==About this Structure==
1JYE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYE OCA].
 
==Reference==
Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator., Bell CE, Barry J, Matthews KS, Lewis M, J Mol Biol. 2001 Oct 12;313(1):99-109. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11601849 11601849]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Barry, J.]]
[[Category: Barry J]]
[[Category: Bell, C E.]]
[[Category: Bell CE]]
[[Category: Lewis, M.]]
[[Category: Lewis M]]
[[Category: Matthews, K S.]]
[[Category: Matthews KS]]
[[Category: Gene regulation]]
[[Category: Protein dna-binding]]
[[Category: Protein stability]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 21:06:12 2008''

Latest revision as of 07:42, 7 February 2024

Structure of a Dimeric Lac Repressor with C-terminal Deletion and K84L Substitution

1jye, resolution 1.70Å

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