1k46: Difference between revisions

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{{Seed}}
[[Image:1k46.png|left|200px]]


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==Crystal Structure of the Type III Secretory Domain of Yersinia YopH Reveals a Domain-Swapped Dimer==
The line below this paragraph, containing "STRUCTURE_1k46", creates the "Structure Box" on the page.
<StructureSection load='1k46' size='340' side='right'caption='[[1k46]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1k46]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pseudotuberculosis Yersinia pseudotuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K46 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k46 OCA], [https://pdbe.org/1k46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k46 RCSB], [https://www.ebi.ac.uk/pdbsum/1k46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k46 ProSAT]</span></td></tr>
{{STRUCTURE_1k46|  PDB=1k46  |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/YOPH_YERPS YOPH_YERPS] Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages.


===Crystal Structure of the Type III Secretory Domain of Yersinia YopH Reveals a Domain-Swapped Dimer===
==See Also==
 
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
 
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[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 11737640 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11737640}}
 
==About this Structure==
1K46 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Yersinia_pseudotuberculosis Yersinia pseudotuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K46 OCA].
 
==Reference==
Structure of the type III secretion and substrate-binding domain of Yersinia YopH phosphatase., Smith CL, Khandelwal P, Keliikuli K, Zuiderweg ER, Saper MA, Mol Microbiol. 2001 Nov;42(4):967-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11737640 11737640]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Single protein]]
[[Category: Yersinia pseudotuberculosis]]
[[Category: Yersinia pseudotuberculosis]]
[[Category: Keliikuli, K.]]
[[Category: Keliikuli K]]
[[Category: Khandelwal, P.]]
[[Category: Khandelwal P]]
[[Category: Saper, M A.]]
[[Category: Saper MA]]
[[Category: Smith, C L.]]
[[Category: Smith CL]]
[[Category: Zuiderweg, E R.P.]]
[[Category: Zuiderweg ERP]]
[[Category: Domain-swap]]
[[Category: Phosphopeptide-binding domain]]
[[Category: Type iii secretion domain]]
 
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Retrieved from "https://proteopedia.org/1k46"