1kh3: Difference between revisions

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{{Seed}}
[[Image:1kh3.png|left|200px]]


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==Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with inhibitor==
The line below this paragraph, containing "STRUCTURE_1kh3", creates the "Structure Box" on the page.
<StructureSection load='1kh3' size='340' side='right'caption='[[1kh3]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1kh3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KH3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KH3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1kh3|  PDB=1kh3  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kh3 OCA], [https://pdbe.org/1kh3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kh3 RCSB], [https://www.ebi.ac.uk/pdbsum/1kh3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kh3 ProSAT], [https://www.topsan.org/Proteins/RSGI/1kh3 TOPSAN]</span></td></tr>
 
</table>
===Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with inhibitor===
== Function ==
 
[https://www.uniprot.org/uniprot/ASSY_THET8 ASSY_THET8]  
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kh/1kh3_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12684518}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1KH3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KH3 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kh3 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Structures of argininosuccinate synthetase in enzyme-ATP substrates and enzyme-AMP product forms: stereochemistry of the catalytic reaction., Goto M, Omi R, Miyahara I, Sugahara M, Hirotsu K, J Biol Chem. 2003 Jun 20;278(25):22964-71. Epub 2003 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12684518 12684518]
</StructureSection>
[[Category: Argininosuccinate synthase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Hirotsu, k.]]
[[Category: Hirotsu k]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Goto m]]
[[Category: Goto, m.]]
[[Category: Miyahara i]]
[[Category: Miyahara, i.]]
[[Category: Ligase]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 10:20:06 2008''