1i7o: Difference between revisions

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New page: left|200px<br /><applet load="1i7o" size="450" color="white" frame="true" align="right" spinBox="true" caption="1i7o, resolution 1.7Å" /> '''CRYSTAL STRUCTURE OF ...
 
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[[Image:1i7o.jpg|left|200px]]<br /><applet load="1i7o" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1i7o, resolution 1.7&Aring;" />
'''CRYSTAL STRUCTURE OF HPCE'''<br />


==About this Structure==
==CRYSTAL STRUCTURE OF HPCE==
1I7O is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with CA as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1I7O OCA].  
<StructureSection load='1i7o' size='340' side='right'caption='[[1i7o]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1i7o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I7O FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i7o OCA], [https://pdbe.org/1i7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i7o RCSB], [https://www.ebi.ac.uk/pdbsum/1i7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i7o ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HPCE_ECOLX HPCE_ECOLX] Decarboxylates OPET (5-oxo-pent-3-ene-1,2,5-tricarboxylic acid) into HHDD (2-hydroxy-hept-2,4-diene-1,7-dioate) and isomerizes it to OHED (2-oxo-hept-3-ene-1,7-dioate).<ref>PMID:8223600</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i7/1i7o_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i7o ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Dodson, E.J.]]
[[Category: Dodson EJ]]
[[Category: Namba, K.]]
[[Category: Namba K]]
[[Category: Roper, D.I.]]
[[Category: Roper DI]]
[[Category: Tame, J.R.H.]]
[[Category: Tame JRH]]
[[Category: CA]]
[[Category: bifunctional enzyme]]
[[Category: decarboxylase]]
[[Category: isomerase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 17:07:45 2007''

Latest revision as of 07:26, 23 October 2024

CRYSTAL STRUCTURE OF HPCE

1i7o, resolution 1.70Å

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