2r19: Difference between revisions

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{{Seed}}
[[Image:2r19.png|left|200px]]


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==Crystal structure of the periplasmic lipopolysaccharide transport protein LptA (YhbN), orthorhombic form==
The line below this paragraph, containing "STRUCTURE_2r19", creates the "Structure Box" on the page.
<StructureSection load='2r19' size='340' side='right'caption='[[2r19]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2r19]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R19 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r19 OCA], [https://pdbe.org/2r19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r19 RCSB], [https://www.ebi.ac.uk/pdbsum/2r19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r19 ProSAT]</span></td></tr>
{{STRUCTURE_2r19|  PDB=2r19  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of the periplasmic lipopolysaccharide transport protein LptA (YhbN), orthorhombic form===
[https://www.uniprot.org/uniprot/LPTA_ECOLI LPTA_ECOLI] Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.[HAMAP-Rule:MF_01914]<ref>PMID:16765569</ref> <ref>PMID:17056748</ref> <ref>PMID:18424520</ref> <ref>PMID:18480051</ref> <ref>PMID:21169485</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_18534617}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 18534617 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/2r19_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_18534617}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r19 ConSurf].
2R19 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R19 OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
Novel structure of the conserved gram-negative lipopolysaccharide transport protein a and mutagenesis analysis., Suits MD, Sperandeo P, Deho G, Polissi A, Jia Z, J Mol Biol. 2008 Jul 11;380(3):476-88. Epub 2008 Apr 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18534617 18534617]
__TOC__
[[Category: Escherichia coli k12]]
</StructureSection>
[[Category: Single protein]]
[[Category: Escherichia coli K-12]]
[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
[[Category: Large Structures]]
[[Category: Jia, Z.]]
[[Category: Jia Z]]
[[Category: Polissi, A.]]
[[Category: Polissi A]]
[[Category: Suits, M D.L.]]
[[Category: Suits MDL]]
[[Category: Beta-jellyroll]]
[[Category: Beta-taco]]
[[Category: Bsgi]]
[[Category: Mainly beta]]
[[Category: Montreal-kingston bacterial structural genomics initiative]]
[[Category: Periplasm]]
[[Category: Structural genomic]]
[[Category: Transport protein]]
 
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Retrieved from "https://proteopedia.org/2r19"