1m0o: Difference between revisions

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{{Seed}}
[[Image:1m0o.png|left|200px]]


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==Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-methylpropanephosphonate==
The line below this paragraph, containing "STRUCTURE_1m0o", creates the "Structure Box" on the page.
<StructureSection load='1m0o' size='340' side='right'caption='[[1m0o]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1m0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M0O FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MPM:(1R)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]-1-METHYLPROPYLPHOSPHONIC+ACID'>MPM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_1m0o|  PDB=1m0o  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m0o OCA], [https://pdbe.org/1m0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m0o RCSB], [https://www.ebi.ac.uk/pdbsum/1m0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m0o ProSAT]</span></td></tr>
 
</table>
===Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-methylpropanephosphonate===
== Function ==
 
[https://www.uniprot.org/uniprot/DGDA_BURCE DGDA_BURCE] The dialkylglycine decarboxylase is of interest because it normally catalyzes both decarboxylation and amino transfer. It may be more properly described as a decarboxylating aminotransferase rather than an aminotransferring decarboxylase.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12369820}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m0/1m0o_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12369820}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1M0O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M0O OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m0o ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Aminophosphonate inhibitors of dialkylglycine decarboxylase: structural basis for slow binding inhibition., Liu W, Rogers CJ, Fisher AJ, Toney MD, Biochemistry. 2002 Oct 15;41(41):12320-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12369820 12369820]
</StructureSection>
[[Category: Burkholderia cepacia]]
[[Category: Burkholderia cepacia]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Fisher, A J.]]
[[Category: Fisher AJ]]
[[Category: Liu, W.]]
[[Category: Liu W]]
[[Category: Rogers, C J.]]
[[Category: Rogers CJ]]
[[Category: Toney, M D.]]
[[Category: Toney MD]]
[[Category: 3d-structure]]
[[Category: Decarboxylase]]
[[Category: Pyridoxal phosphate]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 22:57:34 2008''
Retrieved from "https://proteopedia.org/1m0o"