1m2p: Difference between revisions

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{{Seed}}
[[Image:1m2p.png|left|200px]]


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==Crystal structure of 1,8-di-hydroxy-4-nitro-anthraquinone/CK2 kinase complex==
The line below this paragraph, containing "STRUCTURE_1m2p", creates the "Structure Box" on the page.
<StructureSection load='1m2p' size='340' side='right'caption='[[1m2p]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1m2p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M2P FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HNA:1,8-DI-HYDROXY-4-NITRO-ANTHRAQUINONE'>HNA</scene></td></tr>
{{STRUCTURE_1m2p|  PDB=1m2p |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m2p OCA], [https://pdbe.org/1m2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m2p RCSB], [https://www.ebi.ac.uk/pdbsum/1m2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m2p ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m2/1m2p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m2p ConSurf].
<div style="clear:both"></div>


===Crystal structure of 1,8-di-hydroxy-4-nitro-anthraquinone/CK2 kinase complex===
==See Also==
 
*[[Casein kinase 3D structures|Casein kinase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12419810}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 12419810 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12419810}}
 
==About this Structure==
1M2P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2P OCA].
 
==Reference==
Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight., De Moliner E, Moro S, Sarno S, Zagotto G, Zanotti G, Pinna LA, Battistutta R, J Biol Chem. 2003 Jan 17;278(3):1831-6. Epub 2002 Nov 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12419810 12419810]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Single protein]]
[[Category: Zea mays]]
[[Category: Zea mays]]
[[Category: Battistutta, R.]]
[[Category: Battistutta R]]
[[Category: Moliner, E De.]]
[[Category: De Moliner E]]
[[Category: Moro, S.]]
[[Category: Moro S]]
[[Category: Pinna, L A.]]
[[Category: Pinna LA]]
[[Category: Sarno, S.]]
[[Category: Sarno S]]
[[Category: Zagotto, G.]]
[[Category: Zagotto G]]
[[Category: Zanotti, G.]]
[[Category: Zanotti G]]
[[Category: Inhibitor-enzyme complex]]
[[Category: Kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:05:30 2008''
Retrieved from "https://proteopedia.org/1m2p"