1mb2: Difference between revisions

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{{Seed}}
[[Image:1mb2.png|left|200px]]


<!--
==Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation==
The line below this paragraph, containing "STRUCTURE_1mb2", creates the "Structure Box" on the page.
<StructureSection load='1mb2' size='340' side='right'caption='[[1mb2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mb2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MB2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr>
{{STRUCTURE_1mb2|  PDB=1mb2 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mb2 OCA], [https://pdbe.org/1mb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mb2 RCSB], [https://www.ebi.ac.uk/pdbsum/1mb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mb2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYW_GEOSE SYW_GEOSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mb2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mb2 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation===
==See Also==
 
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12473451}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12473451 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12473451}}
 
==About this Structure==
1MB2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MB2 OCA].
 
==Reference==
Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations., Retailleau P, Huang X, Yin Y, Hu M, Weinreb V, Vachette P, Vonrhein C, Bricogne G, Roversi P, Ilyin V, Carter CW Jr, J Mol Biol. 2003 Jan 3;325(1):39-63. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12473451 12473451]
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Tryptophan--tRNA ligase]]
[[Category: Bricogne G]]
[[Category: Bricogne, G.]]
[[Category: Carter Jr CW]]
[[Category: Hu, M.]]
[[Category: Hu M]]
[[Category: Huang, X.]]
[[Category: Huang X]]
[[Category: Ilyin, V.]]
[[Category: Ilyin V]]
[[Category: Jr., C W.Carter.]]
[[Category: Retailleau P]]
[[Category: Retailleau, P.]]
[[Category: Roversi P]]
[[Category: Roversi, P.]]
[[Category: Vachette P]]
[[Category: Vachette, P.]]
[[Category: Vonrhein C]]
[[Category: Vonrhein, C.]]
[[Category: Weinreb V]]
[[Category: Weinreb, V.]]
[[Category: Yin Y]]
[[Category: Yin, Y.]]
[[Category: Amino acid binding site]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Rossmann fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:36:00 2008''

Latest revision as of 07:42, 14 February 2024

Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation

1mb2, resolution 2.70Å

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