1mbv: Difference between revisions

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{{Seed}}
[[Image:1mbv.png|left|200px]]


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==CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM==
The line below this paragraph, containing "STRUCTURE_1mbv", creates the "Structure Box" on the page.
<StructureSection load='1mbv' size='340' side='right'caption='[[1mbv]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mbv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MBV FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mbv OCA], [https://pdbe.org/1mbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mbv RCSB], [https://www.ebi.ac.uk/pdbsum/1mbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mbv ProSAT]</span></td></tr>
{{STRUCTURE_1mbv| PDB=1mbv |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CLPA_ECOLI CLPA_ECOLI] ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mbv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mbv ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM===
==See Also==
 
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12235156}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12235156 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12235156}}
 
==About this Structure==
1MBV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBV OCA].
 
==Reference==
Crystal structure of the heterodimeric complex of the adaptor, ClpS, with the N-domain of the AAA+ chaperone, ClpA., Guo F, Esser L, Singh SK, Maurizi MR, Xia D, J Biol Chem. 2002 Nov 29;277(48):46753-62. Epub 2002 Sep 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12235156 12235156]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Esser, L.]]
[[Category: Esser L]]
[[Category: Guo, F.]]
[[Category: Guo F]]
[[Category: Maurizi, M R.]]
[[Category: Maurizi MR]]
[[Category: Singh, S K.]]
[[Category: Singh SK]]
[[Category: Xia, D.]]
[[Category: Xia D]]
[[Category: Aaa+ family atp-dependent protease]]
[[Category: Adaptor]]
[[Category: Hsp100/clp chaperone]]
[[Category: Protein binding]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:38:41 2008''

Latest revision as of 07:42, 14 February 2024

CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM

1mbv, resolution 3.30Å

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